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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b74ace9b516b86bf7860adcd34330d43853231c5cce8f8b91361d01df9e6300' 
  AND token = 'ywawSKRnlJeQyOC4zag2G3QXC/gE1MejOOfbkm0d3is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}