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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2271cda4ab8972d7286c9696baec6b0d5b1fd9627de6ec1b8406bb208f99df11' 
  AND token = 'GM/ythe+bd0b1lIPq/OPWsyWfX8N7Ie5+I3sOnWJgXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}