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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561f14dfce7e7b486e1eef8073652b0294f07f6fd162d9b6da60459613307955' 
  AND token = 'H9yhgCaorNvF349LGeLnaHo69NRO2Srg9kIw2cJV2ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}