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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3acf477a9205a39ddc96dfdd683bf71701f43d3d00c4d1742f1d53439ca2ff' 
  AND token = 'I5c7PpgwmNyrd/mJK38MBhxG9ExRcRXQLZAWfJVlTZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}