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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb456a94906a46877a961b86a78ea19023baa114f3373b8fd72a617f747deed' 
  AND token = 'fm49S0QPLm1QXkuiLG5YKNKI41m1kcIZSHtp+ophmjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}