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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517b589d59c25058e31f59edf3b26adfdc64c9a53ce9a1dd05d88f10d27c09e6' 
  AND token = 'I1QAxCnCwgeOv7lTgK9s1WUZVRyu9LeH7FDwTX5RwpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}