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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd967d70bcdff43b79f02fb85d4dce1e9e28c66de4bac8229cbdd4b135286682b' 
  AND token = '7GTD6Tt6v1x3AcjRtuf2GvJn21d6FecB0c3apkcHlqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}