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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '103f9f4c3aae548204e9673bf1ae726c3587cde0ff4d7e005a56f2501ccd2da8' 
  AND token = 'mruJXYG90Ha/gJ0XPIua4fLrzyHDsWUP074ZEgJpZd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}