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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48b20304b874f5ac991584b198dd4af6de0dca1a8586d90ac1abd32223f5403' 
  AND token = 'zCmCjCR4sPM3Dg0pRMCY63Y/UQYPl/TtrGLIC2VYxI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}