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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9447f3b8a99c7a7d7da28fd0f0779c9d811089713d29932b45059ec27f68df8f' 
  AND token = 'DVlUagkhOXB/00PgRAb71l3ZXeE0z4+AbP7HTz1jnz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}