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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5012d6280573999d022ce68f252ea0d11d06e1946b459d63335275a9cd42b3' 
  AND token = '999tH2EBxGHHBWJTouGPv9c8BvciyN8/D7YzVHVnA0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}