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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9b73321261b6c0d73df6f39d34d8997a0f9b2d4bb36f87b11de69110bc7118' 
  AND token = 'hfpZEIJEYfvT6ZBVVrc2Fn8wLMGYPsJNfRPAZtCSKJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}