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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8045342bec65706b7a4a10a998b540edd658a6aecb4670e517cc317f73001c46' 
  AND token = 'k1b323npj3qeSJVZWVnW/CjgGXnOIId28c4U2lMe2hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}