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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33be1e5d41b940a5470a1ff9fc3a749566d928213a24dd62fc684f12c4947912' 
  AND token = 'yx4FeDmcqvJYpyUUipt8IydelF8M9i/lnW8sAHZTuaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}