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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '939261f5ca21591b33511587a0793ea28d037a93de15f9a00ad6320e1581b7e1' 
  AND token = 'PX6G6VIGMIvgg5WrPdUe7qEycMZDcJNtaoLsWxHadJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}