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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b09d7867b6dec0a13fac042f8c5af313a64f19acb324ddec5cee69ffa40e36' 
  AND token = 'RCN31sUiYNSmXeaqNw0TZ1xvQn0GPvNWoE0BhojYKSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}