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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bc0decf1f229d94626a24ddcca76993a3e0a1525888bc60fbb13756bb65386' 
  AND token = 'NQ5aXDaI8/zm1UKWwKVXK8azfY23kdkn5WvV7cT61nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}