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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9d0c5b9ace1f363363af51204a970784d0cab1aa032f1b4c0a3ce7d106ba23' 
  AND token = '5cb+VO+WuPxhPUC86W1zbT3w4RtFdf8K2iGhAZt+FS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}