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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496c22111706d971926a24f9e27ddca296b4b6c6fa126d1c24e0536b739fdb29' 
  AND token = 'uV+qV6XBqRJFM0FNVkiKiaIn7USdq/XJZVHML9z9fho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}