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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6468edf13e2d9cb1996c05ce5354f7a5d7c96d73971c5beca311c5b5b3e7812b' 
  AND token = 'gexIc9vS8IwbWEIgiYEsF/z01l1lKNE0UjMktAXsMQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}