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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '061d5d2cdfe668dd4aed44a5e0a9b89db6188462316bf7a1f3c99560ad7e3400' 
  AND token = 'fuTe7SSSpdF4sFDrjpOw5XLffVvqQcgAeYNtPJ1qKXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}