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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0099c5a1af6d075a601b0211c62d4fb4685d5bccd721153e0bb2fb2e558aac80' 
  AND token = 'kPPlYFuFTcSvsIC4GT/XlgxIsjRQ1tCGKn03SHs4elY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}