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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8d1f26084bf727e4e4f2f86f17bc0b463d35a4849aa9abbb14f4c059ecc579' 
  AND token = 'Z2tVYeBqwhVKc+nUa1yTUueO+RxoKXDC43cXHe9f6fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}