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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c4e517d04af0c0dc9accf410b1d6ed4fc122812b98910ac98a421af5e57321' 
  AND token = 'LGFE5W37qHiFgC+4ZDM2y2xfQ1dgEB6goZZWO5MoOrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}