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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2b8a03d1b25706d79fa93b89d7403fea991582024af3a2c23272b7ca377f51' 
  AND token = 'm+3qIbBvGeWevUx10XrPrR7rB5zsBVyF5lfuGUMBFJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}