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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be95237d756556279885195d3ba1bd4a4956923f20f05a05c634e2cc23ad09b' 
  AND token = 'h2Mzdb5JGyh2PwcnlAPjzYHVsJnN6IGsk2MUSLlyjRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}