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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09b1fb6721bc4a09d6b4b26ca4c0da8881d62a565ebf5d6c36b021ae437be100' 
  AND token = 'SeUq2f6ijksXLb8HdOA544hldt+96mpXJtaT6xCpuhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}