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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aeb2033203ffc8a9825647897d77c8613fd4ffce9aca97fd2fe1775422e7543' 
  AND token = 'JojdtZ0EFnyaXPTYrFyycAiFSSu+232Z21eZNb2wBz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}