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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e8eda6887e2af6d1b588c6c7516081c922a312acb4e614e31610efac0cef17' 
  AND token = 'nmhgyvQPK+kcBDi3mS1P5pJoE7llvw6WTXA8m0XcFEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}