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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd742817b67d5009d6f5bc3357fb38a75beedff88c7c56d9fc09c58aacf287a85' 
  AND token = 'Pr33+CyK8dbnGrAC8ybfcizMb2DV54zHhh1bJG7ZbUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}