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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c2d590595a4ea53a100b2646e4864322753ce2b5d37c1a6bd7b087b11738c5' 
  AND token = 'JfJYPrvCuEFF3c/W+DaUzitZtZYmxOqkhed5fzA2eUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}