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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8599da6c0da8e72d12683a6e37478d9abc979bc5bbf7625ec5041524bc5b4df' 
  AND token = 'gDJb2wYEeDQBwD0b3ZTukX1tBIfNe0c05wsWs1mUc7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}