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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55d94dfbbbc4b47a595f116b9314db417fab830ec500dcb81e3ddac435d35b3' 
  AND token = 'nGczuJbhIR8XdvvqYEsVuhh5wT8SR4fnvtgLmT+7ayY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}