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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268a4a1787625a4a9066b839164f0cab3893faaa53100bf1fa7aec8e804d89b5' 
  AND token = '7WDI1gE+2O8v1x8V/JmHDbrVUriGT5wEh0EVmJi6OB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}