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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a341f08c781e3e2540ebeba7c0708d29af91b5891dc1b09c553a8678958323a8' 
  AND token = 'z2YfKDoJOZDyGwMNWRR+eNxbG9WXTd9ynOdi+Z09L/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}