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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1251f0d2ab270e6006a23f57a8de26fe97112bfee3ecc814001ff113919478d' 
  AND token = 'mcixiR7bBiICcxZG+6VIhWFWBLD03qfpVZ1WVvTx2jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}