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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95bcc388b61958b07cba2011b9eb9af2984fd024c128e03361c181ed0d3361af' 
  AND token = 'F1eIZC08lS4OzTSCzLkfReXiZPYelZ7SxVpMAmcEmRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}