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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1252e150964914007f3c63b596b78b047842b3632614c3dad12fe21be4e39bd0' 
  AND token = 'Ywa7zQ6v/Cr60AOJh2nusJ6yJ8ph61PyFK8UVL031xI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}