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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c034d6b670abce54914f56deb8f733c5253857a832d7cc81d5a70932f1bd9aef' 
  AND token = 'W9k4FO0X1duAxSjf4A87P4xzCMgUKJ1rz6GXdF4d+ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}