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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e0e0a67295391d03967a07fab3612e9a81fb722fa227ad66425e137db4be86' 
  AND token = '5z8kh4tMCpG5BnLR81DdEvfgsUwHaILP2s85bZ4H3R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}