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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9850a26cf28cbab105cc4e01535121b78d8d21da270bd01d83cd57a7bd4047f' 
  AND token = 'GPMyfzROuM/Qq9TZt5rUt4l5XTRyt9vEf6SZb2ul9iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}