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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34277d30c1ea9ee6e0d355cc215348b26a14d22e8615b5fbe54f50a3e81ff897' 
  AND token = 'f3E5LxcSOe8BHgeB1DUZ5BLB0X51wP3eQ64i4Sx7i9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}