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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33391df0435f816717c8ac250b9a6e6f69ee3653f6ea7cc7cb55fd2e2db34d2c' 
  AND token = 'wMswJGfByKWJ6GLLOe7EDX+4NOTwuzshtIP34DuHWOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}