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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2545501351b581b3bb2a452fee4dfb1a7aaceb1687f8154daa002ee4f54e5ca3' 
  AND token = 'ch9s9OgSgpzWxV9mSk38AirdtBZRZrxGI1udUIvsWVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}