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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15832d529fb7715bcf1525f2f565fcd5955cd2eb4c3f02ed0ee014efd9b1da3a' 
  AND token = 'wHfC+YeDSni/h8Em4LLMwdvCbexXOUQwNep+v8Y6Jbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}