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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778fdd22e3627116c528cf44dbabc61075d4557df4a917fb95f36994e169c16b' 
  AND token = 'MPWx8LwdFHdyF2g5WJ4rSp+nJeilVX8EDjkJJcTpR4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}