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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f228c0497682bc805fc2bd18db5c7f146139d31a23f4410589b4af1b9a95319' 
  AND token = '5b5e18pMyKo5oFbpKq1poWOa+o3jUQv8q+zl/gGYSGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}