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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a10d1e754eaf6aac2aea7da2cefa5001007e33b9fcd6343879b157df1d38fe58' 
  AND token = 'ba+vw9iCD63c8g2punemyjJTuREGZrSnR+5pf7fzeZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}