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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ebb4e6c2e576a7ed12dbe91dc513a813fbc2a642cfcb5611df5205fae713591' 
  AND token = 'wzBut7Nqx9bHjPGfj77NJ3RvUS4cEr52i7nTsUN0aL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}