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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10897310fb8a2158ed5434c8379040545d6baad32e690a05138495970a99018' 
  AND token = 'OF+DbFmErUccaIvCeKkG+qKQCqbXGIa9nCi2zB1Wg+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}